Cd41 Antibody Host Rat

Description: A monoclonal antibody for detection of CD41 from Human. This CD41 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Description: A monoclonal antibody for detection of CD41 from Human. This CD41 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Description: A monoclonal antibody for detection of CD41 from Human. This CD41 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Description: CD41 is a protein encoded by the ITGA2B gene which is approximately 113,3 kDa. CD41 is localised to the cell membrane. It is involved in RET signalling, apoptotic pathways, the integrin pathway and focal adhesion. This protein falls under the integrin alpha chain family of proteins. It is a cell-surface receptor that exist as a heterodimer of alpha and beta subunits. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. CD41 is expressed in the bone marrow, lung, spleen, blood and heart. Mutations in the ITGA2B gene may result in glanzmann thrombasthenia. STJ97008 was developed from clone Q90 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous human CD41 protein.

Description: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.

Description: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.

Description: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.